Protein–polymer conjugation — moving beyond PEGylation

Pegylation of Peptides the Case for Peg Conjugation

Moving beyond "noncompliance".

w e all have patients who seem to be “noncom pliant”: the patient with heart failure who misses regular checkups and only comes to the clinic when his prescriptions need renewing, the patient with diabetes who never checks her blood sugars at home, or the patient with hypertension who decides how many blood pressure pills to take each day based on whether she “feels” her blood pressure is high...

Moving Beyond Technical Performance

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Moving beyond "bridges".

Left ventricular assist devices (LVADs) have revolutionized the care of heart failure. They now provide another therapeutic option for many patients, transplant eligible or ineligible, with symptoms refractory to medical therapy and resynchronization therapy. For appropriately selected patients, LVADs offer improvements in both quality and length of life. The enthusiasm for LVAD use in the card...

Moving beyond MTBE.

In March, prompted by rising concerns over groundwater contamination, the U.S. Environmental Protection Agency (EPA) called for a phaseout of methyl-tert-butyl ether, or MTBE, a chemical added to gasoline to reduce carbon monoxide (CO) pollution. The 1990 Clean Air Act requires that gasoline sold in polluted urban areas contain oxygen additives. This "oxygena-tion" supposedly promotes complete ...